STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
CIAPIN1Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (337 aa)    
Predicted Functional Partners:
ENSAPLP00000021445
Flavodoxin-like domain-containing protein.
    
 0.942
GLRX3
Glutaredoxin 3.
    
 
 0.937
NDOR1
NAD_binding_1 domain-containing protein.
    
 0.935
POR
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
    
 0.742
NOS1
Nitric oxide synthase; Produces nitric oxide (NO).
    
 0.742
NOS2
Nitric oxide synthase; Produces nitric oxide (NO).
    
 0.742
MTRR
5-methyltetrahydrofolate-homocysteine methyltransferase reductase.
    
 0.742
NUBP1
Nucleotide binding protein 1.
   
 0.632
CIAO3
Cytosolic iron-sulfur assembly component 3; Belongs to the NARF family.
   
 
 0.626
HSCB
HscB mitochondrial iron-sulfur cluster cochaperone.
      
 0.611
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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