STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DKK2Dickkopf_N domain-containing protein. (348 aa)    
Predicted Functional Partners:
LRP6
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.990
LRP5
Uncharacterized protein.
    
 0.982
KREMEN1
Kringle containing transmembrane protein 1.
    
 0.773
DKK3
Dickkopf WNT signaling pathway inhibitor 3.
      
 0.736
WIF1
WNT inhibitory factor 1.
      
 0.718
SFRP2
Secreted frizzled related protein 2.
     
 0.616
DKK1
Dickkopf WNT signaling pathway inhibitor 1.
     
0.611
SOST
Sclerostin.
      
 0.610
SFRP1
Secreted frizzled related protein 1.
     
 0.606
WNT5A
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
     
 0.556
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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