Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IL12AInterleukin-12 subunit alpha; Belongs to the IL-6 superfamily. (214 aa)    
Predicted Functional Partners:
IL12B
Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily.
    
 0.999
IL12RB2
Interleukin 12 receptor subunit beta 2.
    
 0.993
EBI3
Epstein-Barr virus induced 3.
    
 0.952
IL6ST
Interleukin 6 signal transducer.
    
 0.721
STAT1
Signal transducer and activator of transcription.
    
 0.624
STAT4
Signal transducer and activator of transcription.
    
 0.624
CNTFR
Ciliary neurotrophic factor receptor.
    
 0.584
IL6R
Interleukin 6 receptor.
    
 0.584
JAK1
Tyrosine-protein kinase.
     
 0.564
ENSAPLP00000032274
Protein kinase domain-containing protein.
     
 0.564
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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