Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LYNTyrosine-protein kinase. (535 aa)    
Predicted Functional Partners:
PAG1
Phosphoprotein membrane anchor with glycosphingolipid microdomains 1.
    
 0.939
PTPN6
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
 0.921
PIK3CG
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
   
 0.888
CBL
Cbl proto-oncogene.
    
 0.888
SYK
Spleen associated tyrosine kinase.
   
0.885
LCK
Tyrosine-protein kinase.
   
 0.884
ENSAPLP00000024741
Protein kinase domain-containing protein.
   
 0.884
KHDRBS1
KH RNA binding domain containing, signal transduction associated 1.
    
 0.874
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
   
 0.861
SRMS
Tyrosine-protein kinase.
   
 0.857
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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