WWC3 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

WWC3

WWC family member 3. (1109 aa)

Predicted Functional Partners:

LATS1

0.686

TMEM9

0.638

LATS2

0.632

TMEM9B

0.567

SHROOM2

0.553

FAM102A

0.545

PUDP

0.504

SSRP1

0.485

TSNARE1

0.485

GTPBP6

0.484

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAM102A	WWC3	ENSAPLP00000001437	ENSAPLP00000005782	Family with sequence similarity 102 member A.	WWC family member 3.	0.545
GTPBP6	PUDP	ENSAPLP00000005156	ENSAPLP00000009601	GTP binding protein 6 (putative).	Pseudouridine 5'-phosphatase.	0.642
GTPBP6	WWC3	ENSAPLP00000005156	ENSAPLP00000005782	GTP binding protein 6 (putative).	WWC family member 3.	0.484
LATS1	LATS2	ENSAPLP00000009090	ENSAPLP00000006088	Large tumor suppressor kinase 1.	Non-specific serine/threonine protein kinase.	0.982
LATS1	WWC3	ENSAPLP00000009090	ENSAPLP00000005782	Large tumor suppressor kinase 1.	WWC family member 3.	0.686
LATS2	LATS1	ENSAPLP00000006088	ENSAPLP00000009090	Non-specific serine/threonine protein kinase.	Large tumor suppressor kinase 1.	0.982
LATS2	WWC3	ENSAPLP00000006088	ENSAPLP00000005782	Non-specific serine/threonine protein kinase.	WWC family member 3.	0.632
PUDP	GTPBP6	ENSAPLP00000009601	ENSAPLP00000005156	Pseudouridine 5'-phosphatase.	GTP binding protein 6 (putative).	0.642
PUDP	WWC3	ENSAPLP00000009601	ENSAPLP00000005782	Pseudouridine 5'-phosphatase.	WWC family member 3.	0.504
SHROOM2	SSRP1	ENSAPLP00000016922	ENSAPLP00000015530	Shroom family member 2.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.461
SHROOM2	WWC3	ENSAPLP00000016922	ENSAPLP00000005782	Shroom family member 2.	WWC family member 3.	0.553
SSRP1	SHROOM2	ENSAPLP00000015530	ENSAPLP00000016922	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	Shroom family member 2.	0.461
SSRP1	WWC3	ENSAPLP00000015530	ENSAPLP00000005782	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	WWC family member 3.	0.485
TMEM9	TMEM9B	ENSAPLP00000023944	ENSAPLP00000002924	Transmembrane protein 9.	TMEM9 domain family member B.	0.950
TMEM9	WWC3	ENSAPLP00000023944	ENSAPLP00000005782	Transmembrane protein 9.	WWC family member 3.	0.638
TMEM9B	TMEM9	ENSAPLP00000002924	ENSAPLP00000023944	TMEM9 domain family member B.	Transmembrane protein 9.	0.950
TMEM9B	WWC3	ENSAPLP00000002924	ENSAPLP00000005782	TMEM9 domain family member B.	WWC family member 3.	0.567
TSNARE1	WWC3	ENSAPLP00000030676	ENSAPLP00000005782	t-SNARE domain containing 1.	WWC family member 3.	0.485
WWC3	FAM102A	ENSAPLP00000005782	ENSAPLP00000001437	WWC family member 3.	Family with sequence similarity 102 member A.	0.545
WWC3	GTPBP6	ENSAPLP00000005782	ENSAPLP00000005156	WWC family member 3.	GTP binding protein 6 (putative).	0.484