STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRF5IRF-3 domain-containing protein. (174 aa)    
Predicted Functional Partners:
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.976
ENSAPLP00000030823
C-C motif chemokine.
   
 
 0.903
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.815
TLR7
Toll like receptor 7; Belongs to the Toll-like receptor family.
   
 
 0.612
STAT4
Signal transducer and activator of transcription.
   
 0.582
IL6
Uncharacterized protein.
   
 0.559
IL10
Interleukin 10.
   
 
 0.538
IRAK4
Interleukin 1 receptor associated kinase 4.
   
 0.529
BANK1
B cell scaffold protein with ankyrin repeats 1.
   
  
 0.518
LYN
Tyrosine-protein kinase.
   
 0.517
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (14%) [HD]