TPMT protein (Anas platyrhynchos) - STRING interaction network

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Score

TPMT

Thiopurine S-methyltransferase. (225 aa)

Predicted Functional Partners:

SLC19A1

0.738

GGH

0.703

NUDT15

0.667

DHODH

0.627

COMT

0.580

ITPA

0.560

CD82

0.559

DPYD

0.557

IMPDH2

0.506

SLC16A5

0.462

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD82	TPMT	ENSAPLP00000006208	ENSAPLP00000005925	Tetraspanin.	Thiopurine S-methyltransferase.	0.559
COMT	TPMT	ENSAPLP00000002241	ENSAPLP00000005925	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Thiopurine S-methyltransferase.	0.580
DHODH	DPYD	ENSAPLP00000015086	ENSAPLP00000011867	DHO_dh domain-containing protein.	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	0.462
DHODH	IMPDH2	ENSAPLP00000015086	ENSAPLP00000006641	DHO_dh domain-containing protein.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.732
DHODH	NUDT15	ENSAPLP00000015086	ENSAPLP00000018692	DHO_dh domain-containing protein.	Nudix hydrolase 15.	0.621
DHODH	TPMT	ENSAPLP00000015086	ENSAPLP00000005925	DHO_dh domain-containing protein.	Thiopurine S-methyltransferase.	0.627
DPYD	DHODH	ENSAPLP00000011867	ENSAPLP00000015086	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	DHO_dh domain-containing protein.	0.462
DPYD	ITPA	ENSAPLP00000011867	ENSAPLP00000017648	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	Inosine triphosphatase.	0.429
DPYD	NUDT15	ENSAPLP00000011867	ENSAPLP00000018692	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	Nudix hydrolase 15.	0.736
DPYD	TPMT	ENSAPLP00000011867	ENSAPLP00000005925	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	Thiopurine S-methyltransferase.	0.557
GGH	SLC19A1	ENSAPLP00000010602	ENSAPLP00000003013	Folate gamma-glutamyl hydrolase.	Solute carrier family 19 member 1.	0.851
GGH	TPMT	ENSAPLP00000010602	ENSAPLP00000005925	Folate gamma-glutamyl hydrolase.	Thiopurine S-methyltransferase.	0.703
IMPDH2	DHODH	ENSAPLP00000006641	ENSAPLP00000015086	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	DHO_dh domain-containing protein.	0.732
IMPDH2	ITPA	ENSAPLP00000006641	ENSAPLP00000017648	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Inosine triphosphatase.	0.932
IMPDH2	TPMT	ENSAPLP00000006641	ENSAPLP00000005925	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Thiopurine S-methyltransferase.	0.506
ITPA	DPYD	ENSAPLP00000017648	ENSAPLP00000011867	Inosine triphosphatase.	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.	0.429
ITPA	IMPDH2	ENSAPLP00000017648	ENSAPLP00000006641	Inosine triphosphatase.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.932
ITPA	NUDT15	ENSAPLP00000017648	ENSAPLP00000018692	Inosine triphosphatase.	Nudix hydrolase 15.	0.678
ITPA	TPMT	ENSAPLP00000017648	ENSAPLP00000005925	Inosine triphosphatase.	Thiopurine S-methyltransferase.	0.560
NUDT15	DHODH	ENSAPLP00000018692	ENSAPLP00000015086	Nudix hydrolase 15.	DHO_dh domain-containing protein.	0.621