Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SHANK2SH3 and multiple ankyrin repeat domains 2. (1462 aa)    
Predicted Functional Partners:
DHRS7B
Dehydrogenase/reductase 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
   0.927
DLGAP1
DLG associated protein 1.
   
 0.925
DLGAP2
DLG associated protein 2.
   
 0.914
ENSAPLP00000027683
Uncharacterized protein.
 
  
  0.904
DLGAP3
DLG associated protein 3.
   
 0.800
DLGAP4
DLG associated protein 4.
   
 0.761
HOMER3
WH1 domain-containing protein.
    
 0.720
EHF
ETS homologous factor.
      
 0.719
RILPL1
Rab interacting lysosomal protein like 1.
      
 0.667
ENSAPLP00000018063
Uncharacterized protein; Belongs to the cyclin family.
      
 0.665
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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