U3IFG7_ANAPP protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

U3IFG7_ANAPP

Uncharacterized protein. (438 aa)

Predicted Functional Partners:

RHOA

0.561

RHOC

0.561

RHOB

0.561

RHOT2

0.507

RHOT1

0.507

CFAP70

0.507

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CFAP70	U3IFG7_ANAPP	ENSAPLP00000027109	ENSAPLP00000005989	Cilia and flagella associated protein 70.	Uncharacterized protein.	0.507
RHOA	U3IFG7_ANAPP	ENSAPLP00000014536	ENSAPLP00000005989	Ras homolog family member A.	Uncharacterized protein.	0.561
RHOB	U3IFG7_ANAPP	ENSAPLP00000019696	ENSAPLP00000005989	Ras homolog family member B.	Uncharacterized protein.	0.561
RHOC	U3IFG7_ANAPP	ENSAPLP00000019250	ENSAPLP00000005989	Uncharacterized protein.	Uncharacterized protein.	0.561
RHOT1	U3IFG7_ANAPP	ENSAPLP00000006653	ENSAPLP00000005989	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	Uncharacterized protein.	0.507
RHOT2	U3IFG7_ANAPP	ENSAPLP00000003145	ENSAPLP00000005989	Ras homolog family member T2.	Uncharacterized protein.	0.507
U3IFG7_ANAPP	CFAP70	ENSAPLP00000005989	ENSAPLP00000027109	Uncharacterized protein.	Cilia and flagella associated protein 70.	0.507
U3IFG7_ANAPP	RHOA	ENSAPLP00000005989	ENSAPLP00000014536	Uncharacterized protein.	Ras homolog family member A.	0.561
U3IFG7_ANAPP	RHOB	ENSAPLP00000005989	ENSAPLP00000019696	Uncharacterized protein.	Ras homolog family member B.	0.561
U3IFG7_ANAPP	RHOC	ENSAPLP00000005989	ENSAPLP00000019250	Uncharacterized protein.	Uncharacterized protein.	0.561
U3IFG7_ANAPP	RHOT1	ENSAPLP00000005989	ENSAPLP00000006653	Uncharacterized protein.	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.	0.507
U3IFG7_ANAPP	RHOT2	ENSAPLP00000005989	ENSAPLP00000003145	Uncharacterized protein.	Ras homolog family member T2.	0.507

Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

9 of 260

1.52

2.68

6.80e-10

GO:0042254

Ribosome biogenesis

5 of 236

1.31

1.21

0.00043

GO:0010467

Gene expression

10 of 930

1.01

1.2

1.24e-07

GO:0042274

Ribosomal small subunit biogenesis

3 of 57

1.7

1.17

0.0038

GO:0000028

Ribosomal small subunit assembly

2 of 9

2.33

1.17

0.0067

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

10 of 136

1.85

4.83

2.86e-15

GO:0019843

rRNA binding

3 of 41

1.84

1.16

0.0049

GO:0003723

RNA binding

5 of 485

0.99

0.58

0.0262

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

10 of 151

1.8

4.59

4.30e-15

GO:0022626

Cytosolic ribosome

5 of 68

1.85

2.59

1.15e-06

GO:0044391

Ribosomal subunit

5 of 119

1.6

1.94

1.35e-05

GO:0022625

Cytosolic large ribosomal subunit

3 of 44

1.81

1.39

0.0014

GO:1990904

Ribonucleoprotein complex

6 of 388

1.17

1.16

0.00013

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4256

GTP hydrolysis and joining of the 60S ribosomal subunit

9 of 77

2.05

5.55

8.41e-15

CL:4267

GTP hydrolysis and joining of the 60S ribosomal subunit

8 of 61

2.1

5.48

5.92e-14

CL:4341

Cytosolic small ribosomal subunit, and TNF signaling

4 of 24

2.2

2.92

1.35e-06

CL:4342

Cytosolic small ribosomal subunit, and Ribosomal protein S8

3 of 13

2.34

2.28

4.53e-05

CL:4269

Cytosolic large ribosomal subunit

3 of 34

1.92

1.6

0.00058

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

10 of 150

1.8

4.74

7.79e-16

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72706

GTP hydrolysis and joining of the 60S ribosomal subunit

9 of 90

1.98

5.19

2.03e-14

MAP-72689

Formation of a pool of free 40S subunits

9 of 97

1.95

5.07

2.03e-14

MAP-975956

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

9 of 101

1.93

5.0

2.03e-14

MAP-1799339

SRP-dependent cotranslational protein targeting to membrane

9 of 101

1.93

5.0

2.03e-14

MAP-975957

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

9 of 114

1.88

4.75

3.07e-14

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0022626

Cytosolic ribosome

9 of 73

2.07

5.75

3.34e-15

GOCC:0044391

Ribosomal subunit

9 of 123

1.84

4.47

1.44e-13

GOCC:0022627

Cytosolic small ribosomal subunit

5 of 26

2.26

3.89

1.09e-08

GOCC:1990904

Ribonucleoprotein complex

10 of 363

1.42

2.6

6.79e-12

GOCC:0022625

Cytosolic large ribosomal subunit

4 of 38

2.0

2.48

6.38e-06

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

5 of 60

1.9

2.73

7.42e-07

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