Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RASGRP1RAS guanyl releasing protein 1. (857 aa)    
Predicted Functional Partners:
MRAS
Muscle RAS oncogene homolog.
    
 0.966
RRAS2
RAS related 2.
    
 0.955
RASGRP3
RAS guanyl releasing protein 3.
  
  
0.954
NRAS
Uncharacterized protein.
    
 0.951
HRAS
HRas proto-oncogene, GTPase.
    
 0.951
KRAS
KRAS proto-oncogene, GTPase.
    
 0.951
RAP1B
RAP1B, member of RAS oncogene family.
    
 0.789
RABIF
RAB interacting factor.
      
 0.718
CACNG4
Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
     
 0.685
GPR83
G protein-coupled receptor 83; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.667
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (24%) [HD]