U3IFZ0_ANAPP protein (Anas platyrhynchos) - STRING interaction network

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U3IFZ0_ANAPP

DNA_pol_B_thumb domain-containing protein. (54 aa)

Predicted Functional Partners:

ENSAPLP00000028415

0.941

LIG3

0.929

APEX1

0.854

PARP1

0.814

TDP1

0.814

ENSAPLP00000031478

0.814

LIG1

0.801

XPC

0.800

FEN1

0.798

PCNA

0.781

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APEX1	ENSAPLP00000028415	ENSAPLP00000018420	ENSAPLP00000028415	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	XRCC1_N domain-containing protein.	0.882
APEX1	ENSAPLP00000031478	ENSAPLP00000018420	ENSAPLP00000031478	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	PARP-type domain-containing protein.	0.683
APEX1	FEN1	ENSAPLP00000018420	ENSAPLP00000001147	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.986
APEX1	LIG1	ENSAPLP00000018420	ENSAPLP00000012998	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	DNA ligase.	0.973
APEX1	LIG3	ENSAPLP00000018420	ENSAPLP00000008702	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	DNA ligase.	0.745
APEX1	PARP1	ENSAPLP00000018420	ENSAPLP00000014006	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.683
APEX1	PCNA	ENSAPLP00000018420	ENSAPLP00000028238	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.954
APEX1	TDP1	ENSAPLP00000018420	ENSAPLP00000015477	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	Tyrosyl-DNA phosphodiesterase 1.	0.839
APEX1	U3IFZ0_ANAPP	ENSAPLP00000018420	ENSAPLP00000006162	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	DNA_pol_B_thumb domain-containing protein.	0.854
APEX1	XPC	ENSAPLP00000018420	ENSAPLP00000014092	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	XPC complex subunit, DNA damage recognition and repair factor.	0.445
ENSAPLP00000028415	APEX1	ENSAPLP00000028415	ENSAPLP00000018420	XRCC1_N domain-containing protein.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.882
ENSAPLP00000028415	ENSAPLP00000031478	ENSAPLP00000028415	ENSAPLP00000031478	XRCC1_N domain-containing protein.	PARP-type domain-containing protein.	0.902
ENSAPLP00000028415	FEN1	ENSAPLP00000028415	ENSAPLP00000001147	XRCC1_N domain-containing protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.876
ENSAPLP00000028415	LIG1	ENSAPLP00000028415	ENSAPLP00000012998	XRCC1_N domain-containing protein.	DNA ligase.	0.916
ENSAPLP00000028415	LIG3	ENSAPLP00000028415	ENSAPLP00000008702	XRCC1_N domain-containing protein.	DNA ligase.	0.999
ENSAPLP00000028415	PARP1	ENSAPLP00000028415	ENSAPLP00000014006	XRCC1_N domain-containing protein.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.902
ENSAPLP00000028415	PCNA	ENSAPLP00000028415	ENSAPLP00000028238	XRCC1_N domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.953
ENSAPLP00000028415	TDP1	ENSAPLP00000028415	ENSAPLP00000015477	XRCC1_N domain-containing protein.	Tyrosyl-DNA phosphodiesterase 1.	0.957
ENSAPLP00000028415	U3IFZ0_ANAPP	ENSAPLP00000028415	ENSAPLP00000006162	XRCC1_N domain-containing protein.	DNA_pol_B_thumb domain-containing protein.	0.941
ENSAPLP00000031478	APEX1	ENSAPLP00000031478	ENSAPLP00000018420	PARP-type domain-containing protein.	DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.	0.683