CCKBR protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CCKBR

Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family. (344 aa)

Predicted Functional Partners:

CCK

0.999

GNA14

0.968

GNAQ

0.968

GNB1

0.946

GNB4

0.946

GNB3

0.936

GNB5

0.931

GNG4

0.925

ENSAPLP00000023714

0.925

GNG2

0.925

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCK	CCKBR	ENSAPLP00000000608	ENSAPLP00000006237	Cholecystokinin.	Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.	0.999
CCK	ENSAPLP00000023714	ENSAPLP00000000608	ENSAPLP00000023714	Cholecystokinin.	Gastrin domain-containing protein.	0.545
CCKBR	CCK	ENSAPLP00000006237	ENSAPLP00000000608	Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.	Cholecystokinin.	0.999
CCKBR	ENSAPLP00000023714	ENSAPLP00000006237	ENSAPLP00000023714	Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.	Gastrin domain-containing protein.	0.925
CCKBR	GNA14	ENSAPLP00000006237	ENSAPLP00000004303	Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha 14.	0.968
CCKBR	GNAQ	ENSAPLP00000006237	ENSAPLP00000006398	Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha q.	0.968
CCKBR	GNB1	ENSAPLP00000006237	ENSAPLP00000010816	Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 1.	0.946
CCKBR	GNB3	ENSAPLP00000006237	ENSAPLP00000002795	Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 3.	0.936
CCKBR	GNB4	ENSAPLP00000006237	ENSAPLP00000012022	Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 4.	0.946
CCKBR	GNB5	ENSAPLP00000006237	ENSAPLP00000016983	Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 5.	0.931
CCKBR	GNG2	ENSAPLP00000006237	ENSAPLP00000025803	Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.925
CCKBR	GNG4	ENSAPLP00000006237	ENSAPLP00000005927	Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.925
ENSAPLP00000023714	CCK	ENSAPLP00000023714	ENSAPLP00000000608	Gastrin domain-containing protein.	Cholecystokinin.	0.545
ENSAPLP00000023714	CCKBR	ENSAPLP00000023714	ENSAPLP00000006237	Gastrin domain-containing protein.	Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.	0.925
GNA14	CCKBR	ENSAPLP00000004303	ENSAPLP00000006237	G protein subunit alpha 14.	Cholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family.	0.968
GNA14	GNAQ	ENSAPLP00000004303	ENSAPLP00000006398	G protein subunit alpha 14.	G protein subunit alpha q.	0.901
GNA14	GNB1	ENSAPLP00000004303	ENSAPLP00000010816	G protein subunit alpha 14.	G protein subunit beta 1.	0.880
GNA14	GNB3	ENSAPLP00000004303	ENSAPLP00000002795	G protein subunit alpha 14.	G protein subunit beta 3.	0.848
GNA14	GNB4	ENSAPLP00000004303	ENSAPLP00000012022	G protein subunit alpha 14.	G protein subunit beta 4.	0.880
GNA14	GNB5	ENSAPLP00000004303	ENSAPLP00000016983	G protein subunit alpha 14.	G protein subunit beta 5.	0.710