EMC2 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

EMC2

ER membrane protein complex subunit 2. (395 aa)

Predicted Functional Partners:

EMC3

0.995

EMC6

0.991

EMC1

0.991

EMC7

0.945

MMGT1

0.941

ENSAPLP00000017341

0.922

EMC8

0.922

DERL2

0.787

DCTN4

0.719

ENSAPLP00000026143

0.719

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCTN4	EMC1	ENSAPLP00000000828	ENSAPLP00000023000	Dynactin subunit 4.	Uncharacterized protein.	0.795
DCTN4	EMC2	ENSAPLP00000000828	ENSAPLP00000006264	Dynactin subunit 4.	ER membrane protein complex subunit 2.	0.719
DCTN4	EMC3	ENSAPLP00000000828	ENSAPLP00000000702	Dynactin subunit 4.	ER membrane protein complex subunit 3; Belongs to the EMC3 family.	0.750
DCTN4	EMC6	ENSAPLP00000000828	ENSAPLP00000000067	Dynactin subunit 4.	ER membrane protein complex subunit 6.	0.728
DERL2	EMC1	ENSAPLP00000003476	ENSAPLP00000023000	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Uncharacterized protein.	0.532
DERL2	EMC2	ENSAPLP00000003476	ENSAPLP00000006264	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	ER membrane protein complex subunit 2.	0.787
DERL2	EMC3	ENSAPLP00000003476	ENSAPLP00000000702	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	ER membrane protein complex subunit 3; Belongs to the EMC3 family.	0.751
EMC1	DCTN4	ENSAPLP00000023000	ENSAPLP00000000828	Uncharacterized protein.	Dynactin subunit 4.	0.795
EMC1	DERL2	ENSAPLP00000023000	ENSAPLP00000003476	Uncharacterized protein.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.532
EMC1	EMC2	ENSAPLP00000023000	ENSAPLP00000006264	Uncharacterized protein.	ER membrane protein complex subunit 2.	0.991
EMC1	EMC3	ENSAPLP00000023000	ENSAPLP00000000702	Uncharacterized protein.	ER membrane protein complex subunit 3; Belongs to the EMC3 family.	0.985
EMC1	EMC6	ENSAPLP00000023000	ENSAPLP00000000067	Uncharacterized protein.	ER membrane protein complex subunit 6.	0.963
EMC1	EMC7	ENSAPLP00000023000	ENSAPLP00000025555	Uncharacterized protein.	ER membrane protein complex subunit 7.	0.954
EMC1	EMC8	ENSAPLP00000023000	ENSAPLP00000022473	Uncharacterized protein.	Uncharacterized protein.	0.888
EMC1	ENSAPLP00000017341	ENSAPLP00000023000	ENSAPLP00000017341	Uncharacterized protein.	Uncharacterized protein.	0.888
EMC1	ENSAPLP00000026143	ENSAPLP00000023000	ENSAPLP00000026143	Uncharacterized protein.	Uncharacterized protein.	0.795
EMC1	MMGT1	ENSAPLP00000023000	ENSAPLP00000031659	Uncharacterized protein.	Membrane magnesium transporter 1.	0.927
EMC2	DCTN4	ENSAPLP00000006264	ENSAPLP00000000828	ER membrane protein complex subunit 2.	Dynactin subunit 4.	0.719
EMC2	DERL2	ENSAPLP00000006264	ENSAPLP00000003476	ER membrane protein complex subunit 2.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.787
EMC2	EMC1	ENSAPLP00000006264	ENSAPLP00000023000	ER membrane protein complex subunit 2.	Uncharacterized protein.	0.991