Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EMC2ER membrane protein complex subunit 2. (395 aa)    
Predicted Functional Partners:
EMC3
ER membrane protein complex subunit 3; Belongs to the EMC3 family.
   
 0.995
EMC6
ER membrane protein complex subunit 6.
   
 0.994
EMC7
ER membrane protein complex subunit 7.
   
 0.985
MMGT1
Membrane magnesium transporter 1.
    
 0.985
EMC1
Uncharacterized protein.
   
 0.979
ENSAPLP00000017341
Uncharacterized protein.
   
 0.953
EMC8
Uncharacterized protein.
   
 0.953
DERL2
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 
 0.875
SEC63
SEC63 homolog, protein translocation regulator.
    
 
 0.869
UBAC2
UBA domain containing 2.
    
 
 0.810
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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