Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RELREL proto-oncogene, NF-kB subunit. (592 aa)    
Predicted Functional Partners:
NFKBIA
ANK_REP_REGION domain-containing protein.
   
 0.994
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
    
 0.964
NFKBIE
NFKB inhibitor epsilon.
   
 0.956
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.945
SETD6
SET domain containing 6, protein lysine methyltransferase.
    
 0.926
NFKB2
Nuclear factor kappa B subunit 2.
   
0.926
NFKB1
Nuclear factor kappa B subunit 1.
   
 0.917
EP300
E1A binding protein p300.
    
 0.907
CREBBP
CREB binding protein.
    
 0.899
RPS27A
Ubiquitin-like domain-containing protein.
    
  0.877
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (16%) [HD]