Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
U3IGS0_ANAPPProtein kinase domain-containing protein. (282 aa)    
Predicted Functional Partners:
PAK2
CRIB domain-containing protein.
 
 
  0.998
CDC42
Cell division cycle 42.
   
 0.991
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
   
 0.985
ARHGEF7
Rho guanine nucleotide exchange factor 7.
   
 0.982
NCK2
Cytoplasmic protein.
    
 0.981
RAC1
Rac family small GTPase 1.
   
 0.965
RAC2
Rac family small GTPase 2.
   
 0.963
LIMK2
LIM domain kinase 2.
    
0.956
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
0.956
ENSAPLP00000017111
Protein kinase domain-containing protein.
    
 0.956
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.