Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
U3IGZ7_ANAPPUncharacterized protein. (557 aa)    
Predicted Functional Partners:
RHOA
Ras homolog family member A.
    
 0.938
FYN
Tyrosine-protein kinase.
    
 0.937
YES1
Tyrosine-protein kinase.
    
 0.934
CDC42
Cell division cycle 42.
    
 0.930
RAC1
Rac family small GTPase 1.
    
 0.929
RAC2
Rac family small GTPase 2.
    
 0.929
EGFR
Receptor protein-tyrosine kinase.
    
 0.928
MET
MET proto-oncogene, receptor tyrosine kinase.
   
 0.911
PTPRM
Protein tyrosine phosphatase receptor type M.
   
 0.907
FER
Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
    
 0.906
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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