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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL21Interleukin; Belongs to the IL-15/IL-21 family. (145 aa)    
Predicted Functional Partners:
IL21R
Interleukin 21 receptor.
   
 0.997
IL2RG
Uncharacterized protein.
     
  0.908
IL-17
Uncharacterized protein.
   
  
 0.812
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
  
  
 0.774
IL15
Interleukin; Belongs to the IL-15/IL-21 family.
  
   
 0.768
CD4
Ig-like domain-containing protein.
      
 0.764
STAT3
Signal transducer and activator of transcription.
   
 
 0.758
IL-2
Interleukin; Belongs to the IL-15/IL-21 family.
   
  
 0.756
IL4
Uncharacterized protein.
   
  
 0.750
IL7
Uncharacterized protein.
  
  
 0.734
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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