STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL21Interleukin; Belongs to the IL-15/IL-21 family. (145 aa)    
Predicted Functional Partners:
IL21R
Interleukin 21 receptor.
   
 0.994
IL2RG
Uncharacterized protein.
     
 0.922
IL6
Uncharacterized protein.
      
 0.863
STAT3
Signal transducer and activator of transcription.
    
 0.839
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
  
   
 0.837
IL10
Interleukin 10.
      
 0.819
CD4
Ig-like domain-containing protein.
      
 0.786
ENSAPLP00000020285
IGv domain-containing protein.
  
  
 0.784
IL-17
Uncharacterized protein.
   
  
 0.768
IL7
Uncharacterized protein.
  
   
 0.762
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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