Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEM74Transmembrane protein 74. (275 aa)    
Predicted Functional Partners:
SNAP47
Synaptosome associated protein 47.
      
 0.721
OTOGL
Otogelin like.
      
 0.719
CDADC1
Cytidine and dCMP deaminase domain containing 1.
      
 0.581
U3J7A8_ANAPP
Uncharacterized protein.
      
 0.577
RAB3GAP2
RAB3 GTPase activating non-catalytic protein subunit 2.
      
 0.557
PAK1IP1
PAK1 interacting protein 1.
      
 0.545
BIN3
Bridging integrator 3.
      
 0.482
WDR20
WD repeat domain 20.
      
 0.481
ATG16L1
WD_REPEATS_REGION domain-containing protein.
    
 
 0.474
EIF3E
Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
      
 0.464
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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