STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRHRThyrotropin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (402 aa)    
Predicted Functional Partners:
TRH
Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
     
 0.997
PENK
Proenkephalin.
    
 0.851
PRKDC
Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.
      
 0.850
LYN
Tyrosine-protein kinase.
     
 0.834
CCN3
Cellular communication network factor 3.
      
 0.823
GNA11
G protein subunit alpha 11.
    
 0.816
CALB1
Calbindin 1.
    
 0.783
NTS
Neurotensin.
    
 0.663
EDN1
Endothelin 1.
    
  0.619
TSHB
Thyroid stimulating hormone subunit beta.
     
 0.618
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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