Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KLHDC1Kelch domain containing 1. (404 aa)    
Predicted Functional Partners:
ELOC
Skp1_POZ domain-containing protein; Belongs to the SKP1 family.
    
 0.807
CUL2
Cullin 2; Belongs to the cullin family.
    
 0.801
ENSAPLP00000023149
Uncharacterized protein.
    
 0.712
RBX1
Ring-box 1.
    
 0.698
SLC25A10
Solute carrier family 25 member 10; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.692
CUL5
Cullin 5; Belongs to the cullin family.
    
 0.668
U3IN17_ANAPP
Uncharacterized protein.
      
 0.641
USP1
Ubiquitin specific peptidase 1; Belongs to the peptidase C19 family.
    
 
 0.622
KBTBD13
Kelch repeat and BTB domain containing 13.
      
 0.618
CREB3
Uncharacterized protein.
      
 0.617
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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