STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
U3IHD8_ANAPPUncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1137 aa)    
Predicted Functional Partners:
TGIF2
TGFB induced factor homeobox 2.
    
 
 0.558
ITGAE
Integrin subunit alpha E; Belongs to the integrin alpha chain family.
     
 0.555
ITGA4
Integrin subunit alpha 4; Belongs to the integrin alpha chain family.
     
 0.549
PKP1
Plakophilin 1.
   
 0.537
JUP
Junction plakoglobin.
   
 0.518
PKP3
Plakophilin 3.
   
 0.511
RXFP3
G_PROTEIN_RECEP_F1_2 domain-containing protein.
     
 0.500
PKP2
Plakophilin 2.
   
 0.495
ACOX2
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
    
 
 0.495
ACP2
Acid phosphatase 2, lysosomal; Belongs to the histidine acid phosphatase family.
      
 0.474
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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