Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KIAA0586KIAA0586. (1473 aa)    
Predicted Functional Partners:
ZNF385D
Zinc finger protein 385D.
   
 0.722
TRPC4AP
Transient receptor potential cation channel subfamily C member 4 associated protein.
      
 0.716
CEP120
Centrosomal protein 120.
    
 0.685
CEP290
Centrosomal protein 290.
    
 0.660
DACT1
Dishevelled binding antagonist of beta catenin 1.
      
 0.651
TXNDC12
Thioredoxin domain containing 12.
    
 0.623
CEP97
Centrosomal protein 97.
   
 
 0.600
WDR35
WD repeat domain 35.
      
 0.589
IFT88
Intraflagellar transport 88.
    
 0.585
OFD1
OFD1 centriole and centriolar satellite protein.
   
 0.584
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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