Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MSH3DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1094 aa)    
Predicted Functional Partners:
MSH2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
0.999
MLH1
MutL homolog 1.
 
 0.993
PMS2
PMS1 homolog 2, mismatch repair system component.
 
 0.988
PMS1
PMS1 homolog 1, mismatch repair system component.
 
 0.984
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.971
MSH6
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
0.953
SNX8
Sorting nexin 8.
    
   0.941
EXO1
Exonuclease 1.
   
 0.939
ENSAPLP00000018235
Uncharacterized protein.
 
 0.921
FANCM
FA complementation group M.
    
 
 0.861
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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