Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RIF1Replication timing regulatory factor 1. (2307 aa)    
Predicted Functional Partners:
PAXIP1
PAX interacting protein 1.
   
 0.947
TP53BP1
Tumor protein p53 binding protein 1.
    
 0.922
PPP1CC
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
  0.831
ASF1A
Anti-silencing function 1A histone chaperone.
   
 
 0.821
ATM
Non-specific serine/threonine protein kinase.
   
 0.820
BLM
BLM RecQ like helicase.
   
 
 0.817
U3J2G2_ANAPP
Homeobox domain-containing protein.
    
 
 0.794
BRCA1
BRCA1 DNA repair associated.
   
 0.748
PIAS4
Protein inhibitor of activated STAT 4.
    
 0.716
HEATR1
HEAT repeat containing 1.
   
  
 0.701
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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