Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IGF2RInsulin like growth factor 2 receptor. (2446 aa)    
Predicted Functional Partners:
M6PR
Uncharacterized protein.
     
 0.997
GGA3
Golgi associated, gamma adaptin ear containing, ARF binding protein 3.
    
 
 0.963
IGF2
Insulin like growth factor 2.
    
 
 0.953
VPS26A
VPS26, retromer complex component A.
    
 
 0.898
GAK
Cyclin G associated kinase.
   
 
 0.897
GGA2
Golgi associated, gamma adaptin ear containing, ARF binding protein 2.
    
 
 0.815
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 
 0.815
VTI1A
Vesicle transport through interaction with t-SNAREs 1A.
   
 0.755
SNX8
Sorting nexin 8.
    
 0.753
UFM1
Ubiquitin-fold modifier 1; Ubiquitin-like modifier which can be covalently attached to substrate proteins as a monomer or a lysine-linked polymer in a post- translational process called ufmylation. Ufmylation on lysine residues of proteins may play a crucial role in a number of cellular processes.
      
 0.748
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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