STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRIN3BGlutamate ionotropic receptor NMDA type subunit 3B; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (810 aa)    
Predicted Functional Partners:
GRIN1
Glutamate ionotropic receptor NMDA type subunit 1.
   
0.914
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 0.808
MED16
Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
  
 0.771
GRIN2B
Glutamate ionotropic receptor NMDA type subunit 2B.
     
0.742
ZNF185
LIM zinc-binding domain-containing protein.
      
 0.734
FAM174C
Family with sequence similarity 174 member C.
     
 0.681
RBIS
Ribosomal biogenesis factor.
      
 0.675
ENSAPLP00000019640
Uncharacterized protein.
 
   
 0.663
TLDC2
TLDc domain-containing protein.
      
 0.635
GRIN2A
Glutamate ionotropic receptor NMDA type subunit 2A.
     
0.624
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.