FAN1 protein (Anas platyrhynchos) - STRING interaction network

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FAN1

Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1044 aa)

Predicted Functional Partners:

FANCD2

0.998

MLH1

0.995

PMS2

0.993

FANCI

0.926

PMS1

0.919

FANCM

0.865

MTMR10

0.847

DCLRE1A

0.846

EME1

0.819

SLX1

0.815

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCLRE1A	EME1	ENSAPLP00000013179	ENSAPLP00000022319	DNA cross-link repair 1A.	Essential meiotic structure-specific endonuclease 1.	0.876
DCLRE1A	FAN1	ENSAPLP00000013179	ENSAPLP00000006932	DNA cross-link repair 1A.	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.846
DCLRE1A	FANCD2	ENSAPLP00000013179	ENSAPLP00000022164	DNA cross-link repair 1A.	Uncharacterized protein.	0.869
DCLRE1A	FANCI	ENSAPLP00000013179	ENSAPLP00000004594	DNA cross-link repair 1A.	FA complementation group I.	0.843
DCLRE1A	FANCM	ENSAPLP00000013179	ENSAPLP00000027475	DNA cross-link repair 1A.	FA complementation group M.	0.836
DCLRE1A	SLX1	ENSAPLP00000013179	ENSAPLP00000031903	DNA cross-link repair 1A.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	0.741
EME1	DCLRE1A	ENSAPLP00000022319	ENSAPLP00000013179	Essential meiotic structure-specific endonuclease 1.	DNA cross-link repair 1A.	0.876
EME1	FAN1	ENSAPLP00000022319	ENSAPLP00000006932	Essential meiotic structure-specific endonuclease 1.	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	0.819
EME1	FANCD2	ENSAPLP00000022319	ENSAPLP00000022164	Essential meiotic structure-specific endonuclease 1.	Uncharacterized protein.	0.886
EME1	FANCI	ENSAPLP00000022319	ENSAPLP00000004594	Essential meiotic structure-specific endonuclease 1.	FA complementation group I.	0.882
EME1	FANCM	ENSAPLP00000022319	ENSAPLP00000027475	Essential meiotic structure-specific endonuclease 1.	FA complementation group M.	0.865
EME1	MLH1	ENSAPLP00000022319	ENSAPLP00000025394	Essential meiotic structure-specific endonuclease 1.	MutL homolog 1.	0.453
EME1	SLX1	ENSAPLP00000022319	ENSAPLP00000031903	Essential meiotic structure-specific endonuclease 1.	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.	0.949
FAN1	DCLRE1A	ENSAPLP00000006932	ENSAPLP00000013179	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	DNA cross-link repair 1A.	0.846
FAN1	EME1	ENSAPLP00000006932	ENSAPLP00000022319	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Essential meiotic structure-specific endonuclease 1.	0.819
FAN1	FANCD2	ENSAPLP00000006932	ENSAPLP00000022164	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Uncharacterized protein.	0.998
FAN1	FANCI	ENSAPLP00000006932	ENSAPLP00000004594	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	FA complementation group I.	0.926
FAN1	FANCM	ENSAPLP00000006932	ENSAPLP00000027475	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	FA complementation group M.	0.865
FAN1	MLH1	ENSAPLP00000006932	ENSAPLP00000025394	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	MutL homolog 1.	0.995
FAN1	MTMR10	ENSAPLP00000006932	ENSAPLP00000006371	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Myotubularin related protein 10.	0.847

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