STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WDFY2WD repeat and FYVE domain containing 2. (400 aa)    
Predicted Functional Partners:
GTF2F2
General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.
    
 0.832
U3IAG5_ANAPP
Fibrinogen C-terminal domain-containing protein.
      
 0.747
SPERT
Uncharacterized protein.
    
 0.676
PDZD11
PDZ domain containing 11.
    
 0.675
AP1S3
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
 
      0.662
TBC1D31
TBC1 domain family member 31.
     
 0.650
SERPINE3
Serpin family E member 3; Belongs to the serpin family.
 
  
 
 0.638
INTS6
Integrator complex subunit 6.
     
 0.632
NEK3
NIMA related kinase 3; Belongs to the protein kinase superfamily.
   
 0.625
AP1S2
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
 
      0.622
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.