Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CAP2Adenylyl cyclase-associated protein; Belongs to the CAP family. (478 aa)    
Predicted Functional Partners:
WDR1
WD repeat domain 1.
   
 
 0.821
PFN4
Profilin; Belongs to the profilin family.
   
 0.805
PFN2
Profilin; Belongs to the profilin family.
   
 0.707
DSTN
Destrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family.
   
 0.703
CFL2
Cofilin 2; Belongs to the actin-binding proteins ADF family.
   
 0.703
GRXCR1
Glutaredoxin and cysteine rich domain containing 1.
    
   0.688
BCL7A
BAF chromatin remodeling complex subunit BCL7A.
    
   0.681
CAPZB
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.677
URB2
URB2 ribosome biogenesis homolog.
   
 0.660
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2.
    
 
 0.654
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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