Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DEPDC5DEP domain-containing protein. (870 aa)    
Predicted Functional Partners:
NPRL3
NPR3 like, GATOR1 complex subunit.
   
 0.997
NPRL2
NPR2 like, GATOR1 complex subunit.
    
 0.996
MIOS
Meiosis regulator for oocyte development.
    
 0.995
WDR24
WD repeat domain 24.
   
 0.995
WDR59
WD repeat domain 59.
   
 0.994
RRAGB
Ras related GTP binding B.
    
 0.991
SEC13
SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.
    
 0.989
SEH1L
SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family.
    
 0.988
ENSAPLP00000028801
Uncharacterized protein.
 
  
  0.968
C12orf66
Chromosome 12 open reading frame 66.
   
 0.946
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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