Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TERF2Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (514 aa)    
Predicted Functional Partners:
TERF2IP
TERF2 interacting protein.
   
 0.998
POT1
Protection of telomeres 1.
   
 0.996
ENSAPLP00000025377
Uncharacterized protein.
   
 0.990
TERF1
Telomeric repeat binding factor 1.
   
0.982
MRE11
MRE11 homolog, double strand break repair nuclease.
    
 0.975
NBN
Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
    
 0.973
SLX4
SLX4 structure-specific endonuclease subunit.
    
 
 0.967
ENSAPLP00000026881
Zinc-hook domain-containing protein.
    
 0.948
XRCC6
X-ray repair cross complementing 6.
    
 
 0.895
BLM
BLM RecQ like helicase.
    
 0.891
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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