Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)    
Predicted Functional Partners:
PRKAB1
Protein kinase AMP-activated non-catalytic subunit beta 1.
   
 0.999
PRKAB2
Protein kinase AMP-activated non-catalytic subunit beta 2.
   
 0.999
PRKAA1
Non-specific serine/threonine protein kinase.
  
0.994
PRKAG1
Protein kinase AMP-activated non-catalytic subunit gamma 1.
   
 0.993
PRKAG3
Protein kinase AMP-activated non-catalytic subunit gamma 3.
   
 0.990
STK11
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
    
0.988
PRKAG2
Protein kinase AMP-activated non-catalytic subunit gamma 2.
   
 0.987
TSC2
TSC complex subunit 2.
    
 0.986
MTOR
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
 0.985
TSC1
TSC complex subunit 1.
    
 0.971
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (24%) [HD]