Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
FAM45AUDENN domain-containing protein. (354 aa)    
Predicted Functional Partners:
COMMD8
COMM domain containing 8.
    
 
 0.979
COMMD4
COMM domain containing 4.
    
 
 0.979
U3IYV3_ANAPP
COMM domain-containing protein.
    
 
 0.979
COMMD2
COMM domain containing 2.
    
 
 0.979
VPS35L
VPS35 endosomal protein sorting factor like.
    
 
 0.978
CCDC93
Coiled-coil domain containing 93.
    
 
 0.975
VPS26C
VPS26 endosomal protein sorting factor C.
    
 
 0.974
U3IBJ8_ANAPP
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
   
 
 0.973
COMMD1
Copper metabolism domain containing 1.
   
 
 0.973
COMMD6
COMM domain containing 6.
   
 
 0.966
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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