| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSAPLP00000025456 | UCP3 | ENSAPLP00000025456 | ENSAPLP00000007174 | Uncharacterized protein. | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.594 |
| FARS2 | UCP3 | ENSAPLP00000018500 | ENSAPLP00000007174 | Phenylalanyl-tRNA synthetase 2, mitochondrial. | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.556 |
| GET1 | UCP3 | ENSAPLP00000023788 | ENSAPLP00000007174 | Guided entry of tail-anchored proteins factor 1. | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.594 |
| GPAT4 | PPARA | ENSAPLP00000017169 | ENSAPLP00000010405 | Glycerol-3-phosphate acyltransferase 4. | Peroxisome proliferator activated receptor alpha. | 0.570 |
| GPAT4 | UCP3 | ENSAPLP00000017169 | ENSAPLP00000007174 | Glycerol-3-phosphate acyltransferase 4. | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.511 |
| INS | PDK4 | ENSAPLP00000012854 | ENSAPLP00000015574 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Protein-serine/threonine kinase. | 0.479 |
| INS | PPARA | ENSAPLP00000012854 | ENSAPLP00000010405 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Peroxisome proliferator activated receptor alpha. | 0.669 |
| INS | PPARG | ENSAPLP00000012854 | ENSAPLP00000008758 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.798 |
| INS | PPARGC1A | ENSAPLP00000012854 | ENSAPLP00000031219 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | PPARG coactivator 1 alpha. | 0.578 |
| INS | UCP3 | ENSAPLP00000012854 | ENSAPLP00000007174 | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.586 |
| PDK4 | INS | ENSAPLP00000015574 | ENSAPLP00000012854 | Protein-serine/threonine kinase. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.479 |
| PDK4 | PPARG | ENSAPLP00000015574 | ENSAPLP00000008758 | Protein-serine/threonine kinase. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.524 |
| PDK4 | UCP3 | ENSAPLP00000015574 | ENSAPLP00000007174 | Protein-serine/threonine kinase. | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.539 |
| PPARA | GPAT4 | ENSAPLP00000010405 | ENSAPLP00000017169 | Peroxisome proliferator activated receptor alpha. | Glycerol-3-phosphate acyltransferase 4. | 0.570 |
| PPARA | INS | ENSAPLP00000010405 | ENSAPLP00000012854 | Peroxisome proliferator activated receptor alpha. | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.669 |
| PPARA | PPARGC1A | ENSAPLP00000010405 | ENSAPLP00000031219 | Peroxisome proliferator activated receptor alpha. | PPARG coactivator 1 alpha. | 0.941 |
| PPARA | UCP3 | ENSAPLP00000010405 | ENSAPLP00000007174 | Peroxisome proliferator activated receptor alpha. | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.459 |
| PPARG | INS | ENSAPLP00000008758 | ENSAPLP00000012854 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.798 |
| PPARG | PDK4 | ENSAPLP00000008758 | ENSAPLP00000015574 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | Protein-serine/threonine kinase. | 0.524 |
| PPARG | PPARGC1A | ENSAPLP00000008758 | ENSAPLP00000031219 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | PPARG coactivator 1 alpha. | 0.967 |