| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACADM | PPARG | ENSAPLP00000030012 | ENSAPLP00000008758 | Acyl-CoA dehydrogenase medium chain. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.484 |
| ACADM | PPARGC1A | ENSAPLP00000030012 | ENSAPLP00000031219 | Acyl-CoA dehydrogenase medium chain. | PPARG coactivator 1 alpha. | 0.420 |
| ACADM | UCP3 | ENSAPLP00000030012 | ENSAPLP00000007174 | Acyl-CoA dehydrogenase medium chain. | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.667 |
| ENSAPLP00000020487 | PPARGC1A | ENSAPLP00000020487 | ENSAPLP00000031219 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. | PPARG coactivator 1 alpha. | 0.435 |
| ENSAPLP00000020487 | UCP3 | ENSAPLP00000020487 | ENSAPLP00000007174 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.668 |
| GPAT4 | PCK1 | ENSAPLP00000017169 | ENSAPLP00000002378 | Glycerol-3-phosphate acyltransferase 4. | Phosphoenolpyruvate carboxykinase 1. | 0.601 |
| GPAT4 | UCP3 | ENSAPLP00000017169 | ENSAPLP00000007174 | Glycerol-3-phosphate acyltransferase 4. | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.769 |
| PCK1 | GPAT4 | ENSAPLP00000002378 | ENSAPLP00000017169 | Phosphoenolpyruvate carboxykinase 1. | Glycerol-3-phosphate acyltransferase 4. | 0.601 |
| PCK1 | PPARG | ENSAPLP00000002378 | ENSAPLP00000008758 | Phosphoenolpyruvate carboxykinase 1. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.500 |
| PCK1 | PPARGC1A | ENSAPLP00000002378 | ENSAPLP00000031219 | Phosphoenolpyruvate carboxykinase 1. | PPARG coactivator 1 alpha. | 0.715 |
| PCK1 | TLR4 | ENSAPLP00000002378 | ENSAPLP00000012401 | Phosphoenolpyruvate carboxykinase 1. | Toll like receptor 4. | 0.667 |
| PCK1 | UCP3 | ENSAPLP00000002378 | ENSAPLP00000007174 | Phosphoenolpyruvate carboxykinase 1. | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.668 |
| PPARG | ACADM | ENSAPLP00000008758 | ENSAPLP00000030012 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | Acyl-CoA dehydrogenase medium chain. | 0.484 |
| PPARG | PCK1 | ENSAPLP00000008758 | ENSAPLP00000002378 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | Phosphoenolpyruvate carboxykinase 1. | 0.500 |
| PPARG | PPARGC1A | ENSAPLP00000008758 | ENSAPLP00000031219 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | PPARG coactivator 1 alpha. | 0.991 |
| PPARG | TLR4 | ENSAPLP00000008758 | ENSAPLP00000012401 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | Toll like receptor 4. | 0.617 |
| PPARG | TMEM26 | ENSAPLP00000008758 | ENSAPLP00000010320 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | Transmembrane protein 26. | 0.409 |
| PPARG | UCP3 | ENSAPLP00000008758 | ENSAPLP00000007174 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.675 |
| PPARGC1A | ACADM | ENSAPLP00000031219 | ENSAPLP00000030012 | PPARG coactivator 1 alpha. | Acyl-CoA dehydrogenase medium chain. | 0.420 |
| PPARGC1A | ENSAPLP00000020487 | ENSAPLP00000031219 | ENSAPLP00000020487 | PPARG coactivator 1 alpha. | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. | 0.435 |