Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C5Complement C5. (880 aa)    
Predicted Functional Partners:
C8A
Complement C8 alpha chain.
   
 0.969
C7
Complement C7.
   
 0.967
C9
Complement C9.
   
 0.966
C3
Complement C3.
   
0.958
U3HZZ8_ANAPP
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
    
 0.824
C3AR1
Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.824
ENSAPLP00000017767
G_PROTEIN_RECEP_F1_2 domain-containing protein.
    
 0.824
F2
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 0.782
CFI
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 0.723
TRAF1
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
 
    
 0.716
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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