HSF1 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

HSF1

Heat shock transcription factor 1. (450 aa)

Predicted Functional Partners:

PTGES3

0.907

HSBP1

0.821

HSPA8

0.741

TSC1

0.705

FBXL8

0.648

GSK3B

0.637

MAPK1

0.636

EEF1A1

0.630

HSP90AA1

0.624

ENSAPLP00000021501

0.624

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEF1A1	ENSAPLP00000021501	ENSAPLP00000017162	ENSAPLP00000021501	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	HATPase_c domain-containing protein.	0.406
EEF1A1	HSF1	ENSAPLP00000017162	ENSAPLP00000007293	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Heat shock transcription factor 1.	0.630
EEF1A1	HSP90AA1	ENSAPLP00000017162	ENSAPLP00000017253	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Uncharacterized protein.	0.406
ENSAPLP00000021501	EEF1A1	ENSAPLP00000021501	ENSAPLP00000017162	HATPase_c domain-containing protein.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.406
ENSAPLP00000021501	HSBP1	ENSAPLP00000021501	ENSAPLP00000021864	HATPase_c domain-containing protein.	Heat shock factor binding protein 1.	0.444
ENSAPLP00000021501	HSF1	ENSAPLP00000021501	ENSAPLP00000007293	HATPase_c domain-containing protein.	Heat shock transcription factor 1.	0.624
ENSAPLP00000021501	HSP90AA1	ENSAPLP00000021501	ENSAPLP00000017253	HATPase_c domain-containing protein.	Uncharacterized protein.	0.951
ENSAPLP00000021501	HSPA8	ENSAPLP00000021501	ENSAPLP00000027211	HATPase_c domain-containing protein.	Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family.	0.853
ENSAPLP00000021501	MAPK1	ENSAPLP00000021501	ENSAPLP00000005723	HATPase_c domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.424
ENSAPLP00000021501	PTGES3	ENSAPLP00000021501	ENSAPLP00000028684	HATPase_c domain-containing protein.	Prostaglandin E synthase 3.	0.910
FBXL8	HSF1	ENSAPLP00000025693	ENSAPLP00000007293	F-box domain-containing protein.	Heat shock transcription factor 1.	0.648
GSK3B	HSF1	ENSAPLP00000026002	ENSAPLP00000007293	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Heat shock transcription factor 1.	0.637
GSK3B	TSC1	ENSAPLP00000026002	ENSAPLP00000001959	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	TSC complex subunit 1.	0.935
HSBP1	ENSAPLP00000021501	ENSAPLP00000021864	ENSAPLP00000021501	Heat shock factor binding protein 1.	HATPase_c domain-containing protein.	0.444
HSBP1	HSF1	ENSAPLP00000021864	ENSAPLP00000007293	Heat shock factor binding protein 1.	Heat shock transcription factor 1.	0.821
HSBP1	HSP90AA1	ENSAPLP00000021864	ENSAPLP00000017253	Heat shock factor binding protein 1.	Uncharacterized protein.	0.444
HSBP1	HSPA8	ENSAPLP00000021864	ENSAPLP00000027211	Heat shock factor binding protein 1.	Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family.	0.452
HSBP1	TSC1	ENSAPLP00000021864	ENSAPLP00000001959	Heat shock factor binding protein 1.	TSC complex subunit 1.	0.440
HSF1	EEF1A1	ENSAPLP00000007293	ENSAPLP00000017162	Heat shock transcription factor 1.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.630
HSF1	ENSAPLP00000021501	ENSAPLP00000007293	ENSAPLP00000021501	Heat shock transcription factor 1.	HATPase_c domain-containing protein.	0.624