Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HSF1Heat shock transcription factor 1. (450 aa)    
Predicted Functional Partners:
HSPA8
Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family.
    
 0.803
ENSAPLP00000021501
HATPase_c domain-containing protein.
    
 0.797
HSPA4
Heat shock protein family A (Hsp70) member 4.
   
 0.739
HSBP1
Heat shock factor binding protein 1.
    
 0.718
HSPA2
Heat shock protein family A (Hsp70) member 2.
    
 0.706
STUB1
STIP1 homology and U-box containing protein 1.
   
 0.700
PTGES3
Prostaglandin E synthase 3.
    
 0.698
HSP90AA1
Uncharacterized protein.
    
 0.697
ENSAPLP00000025272
Uncharacterized protein.
    
 0.697
TSC1
TSC complex subunit 1.
    
 0.696
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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