STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRP2LDL receptor related protein 2. (4583 aa)    
Predicted Functional Partners:
PTCH1
Patched 1.
    
 0.920
SHH
Sonic hedgehog signaling molecule.
     
 0.919
CDON
Cell adhesion associated, oncogene regulated.
     
 0.919
PTCH2
SSD domain-containing protein.
    
 0.907
BOC
BOC cell adhesion associated, oncogene regulated.
     
 0.906
DHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
     
 0.903
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
     
 0.903
LDLRAP1
Low density lipoprotein receptor adaptor protein 1.
    
 0.890
MUSK
Muscle associated receptor tyrosine kinase.
   
 0.845
AGRN
Agrin.
    
 0.781
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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