STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERN1Endoplasmic reticulum to nucleus signaling 1. (958 aa)    
Predicted Functional Partners:
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.938
MAP3K5
Mitogen-activated protein kinase kinase kinase 5.
   
0.930
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
    
 0.914
AMFR
Autocrine motility factor receptor.
    
 
 0.655
ABCE1
ATP binding cassette subfamily E member 1.
   
 0.646
UBFD1
Ubiquitin family domain containing 1.
 
  
 0.562
XBP1
X-box binding protein 1.
    
 0.530
SEC63
SEC63 homolog, protein translocation regulator.
    
 
 0.498
EDEM1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
    
 
 0.466
ATF6
Activating transcription factor 6.
    
 
 0.456
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.