Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HTTHuntingtin. (3080 aa)    
Predicted Functional Partners:
VCP
Valosin containing protein; Belongs to the AAA ATPase family.
   
 0.958
CREBBP
CREB binding protein.
   
 0.957
HIP1
Huntingtin interacting protein 1.
    
 
 0.929
OPTN
Optineurin.
    
 
 0.927
TRAK1
Trafficking kinesin protein 1.
    
 
 0.915
SNCA
Alpha-synuclein; Belongs to the synuclein family.
   
 
 0.900
HYPK
Huntingtin interacting protein K.
    
 
 0.890
HIP1R
Huntingtin interacting protein 1 related.
    
 
 0.888
SQSTM1
Uncharacterized protein.
    
 
 0.884
PRPF40A
Pre-mRNA processing factor 40 homolog A.
   
 0.871
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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