Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
U3IK07_ANAPPProline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (605 aa)    
Predicted Functional Partners:
PYCR3
P5CR_dimer domain-containing protein.
   
 0.930
PYCR1
P5CR_dimer domain-containing protein.
   
 0.930
P4HA2
Prolyl 4-hydroxylase subunit alpha 2.
   
 
 0.906
P4HA1
Prolyl 4-hydroxylase subunit alpha 1.
   
 
 0.906
P4HA3
P4Ha_N domain-containing protein.
   
 
 0.906
LAP3
Leucine aminopeptidase 3.
     
  0.900
U3IT68_ANAPP
Aldedh domain-containing protein.
  
 0.766
ALDH4A1
Aldedh domain-containing protein.
  
 0.766
OAT
Ornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.748
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
   
 
 0.692
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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