Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (512 aa)    
Predicted Functional Partners:
CH25H
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
   
 0.969
U3HZ43_ANAPP
3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family.
   
 0.955
U3IP70_ANAPP
Uncharacterized protein.
   
 0.955
CYP46A1
Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family.
  
 
0.952
ENSAPLP00000030316
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
 
 0.945
U3IEM6_ANAPP
Uncharacterized protein; Belongs to the cytochrome P450 family.
  
 
 0.943
U3IRP6_ANAPP
Sulfotransferase; Belongs to the sulfotransferase 1 family.
   
 
 0.943
CYP27A1
Cytochrome P450 family 27 subfamily A member 1.
   
 0.942
DHCR7
7-dehydrocholesterol reductase.
   
 0.930
SOAT1
O-acyltransferase.
   
 
 0.929
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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