node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COX11 | SLC19A3 | ENSAPLP00000027818 | ENSAPLP00000007778 | Cytochrome c oxidase copper chaperone COX11. | Solute carrier family 19 member 3. | 0.483 |
COX11 | SLC9A3 | ENSAPLP00000027818 | ENSAPLP00000019235 | Cytochrome c oxidase copper chaperone COX11. | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | 0.485 |
DAW1 | SLC19A3 | ENSAPLP00000007890 | ENSAPLP00000007778 | WD_REPEATS_REGION domain-containing protein. | Solute carrier family 19 member 3. | 0.608 |
ENSAPLP00000031682 | LIAS | ENSAPLP00000031682 | ENSAPLP00000011673 | Nfu_N domain-containing protein. | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.657 |
ENSAPLP00000031682 | LIPT1 | ENSAPLP00000031682 | ENSAPLP00000001416 | Nfu_N domain-containing protein. | Lipoyltransferase 1. | 0.611 |
ENSAPLP00000031682 | PDHX | ENSAPLP00000031682 | ENSAPLP00000011507 | Nfu_N domain-containing protein. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.552 |
ENSAPLP00000031682 | SLC19A3 | ENSAPLP00000031682 | ENSAPLP00000007778 | Nfu_N domain-containing protein. | Solute carrier family 19 member 3. | 0.478 |
ENSAPLP00000031682 | SLC25A19 | ENSAPLP00000031682 | ENSAPLP00000019299 | Nfu_N domain-containing protein. | Solute carrier family 25 member 19; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.602 |
ENSAPLP00000031682 | SUCLA2 | ENSAPLP00000031682 | ENSAPLP00000008130 | Nfu_N domain-containing protein. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.482 |
ENSAPLP00000031682 | TPK1 | ENSAPLP00000031682 | ENSAPLP00000032069 | Nfu_N domain-containing protein. | Thiamin pyrophosphokinase 1. | 0.551 |
LIAS | ENSAPLP00000031682 | ENSAPLP00000011673 | ENSAPLP00000031682 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Nfu_N domain-containing protein. | 0.657 |
LIAS | LIPT1 | ENSAPLP00000011673 | ENSAPLP00000001416 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Lipoyltransferase 1. | 0.995 |
LIAS | PDHX | ENSAPLP00000011673 | ENSAPLP00000011507 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.654 |
LIAS | SLC19A3 | ENSAPLP00000011673 | ENSAPLP00000007778 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Solute carrier family 19 member 3. | 0.518 |
LIAS | SLC25A19 | ENSAPLP00000011673 | ENSAPLP00000019299 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Solute carrier family 25 member 19; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.613 |
LIAS | SUCLA2 | ENSAPLP00000011673 | ENSAPLP00000008130 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.464 |
LIAS | TPK1 | ENSAPLP00000011673 | ENSAPLP00000032069 | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | Thiamin pyrophosphokinase 1. | 0.611 |
LIPT1 | ENSAPLP00000031682 | ENSAPLP00000001416 | ENSAPLP00000031682 | Lipoyltransferase 1. | Nfu_N domain-containing protein. | 0.611 |
LIPT1 | LIAS | ENSAPLP00000001416 | ENSAPLP00000011673 | Lipoyltransferase 1. | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.995 |
LIPT1 | PDHX | ENSAPLP00000001416 | ENSAPLP00000011507 | Lipoyltransferase 1. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. | 0.886 |