Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SLC19A3Solute carrier family 19 member 3. (510 aa)    
Predicted Functional Partners:
SLC19A2
Solute carrier family 19 member 2.
  
  
0.910
ATP5F1B
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
    
 
 0.680
TPK1
Thiamin pyrophosphokinase 1.
      
 0.678
SLC25A19
Solute carrier family 25 member 19; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.546
MCCC1
Methylcrotonoyl-CoA carboxylase 1.
      
 0.483
HLCS
Holocarboxylase synthetase.
      
 0.483
PCCA
Propionyl-CoA carboxylase subunit alpha.
      
 0.483
MCCC2
Methylcrotonoyl-CoA carboxylase 2.
      
 0.483
BCKDHA
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
      
 0.480
PDHX
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
      
 0.464
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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