Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIX1SIX homeobox 1. (282 aa)    
Predicted Functional Partners:
EYA1
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 0.830
EYA2
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 0.808
EYA3
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 0.793
EYA4
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 0.652
HOXA5
Homeobox A5.
    
 
 0.548
MYF5
Myogenic factor.
   
 
 0.528
PAX2
Paired box 2.
    
 0.465
PAX7
Paired box 7.
   
 
 0.459
HOXB7
Homeobox B7.
    
 
 0.421
PAX5
Paired box 5.
    
 0.411
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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