Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ITM2BIntegral membrane protein 2B. (263 aa)    
Predicted Functional Partners:
APP
Amyloid beta precursor protein.
   
 0.847
GNAL
G protein subunit alpha L.
   
 
 0.764
APLP2
Amyloid beta precursor like protein 2.
   
 0.688
SCAMP1
Secretory carrier-associated membrane protein.
    
 
 0.656
CD74
CD74 molecule.
   
 
 0.633
MLNR
Motilin receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.630
CYSLTR2
Cysteinyl leukotriene receptor 2.
      
 0.622
CDADC1
Cytidine and dCMP deaminase domain containing 1.
      
 0.622
HOXB6
Homeobox B6.
      
 0.613
UBE2C
Ubiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family.
   
  
 0.604
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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