close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITM2BIntegral membrane protein 2B. (263 aa)    
Predicted Functional Partners:
U3IWR7_ANAPP
Uncharacterized protein.
   
  
 0.629
SPRYD7
SPRY domain containing 7.
      
 0.611
RCBTB2
RCC1 and BTB domain containing protein 2.
      
 0.611
AFAP1L1
Actin filament associated protein 1 like 1.
      
 0.611
TBC1D8B
TBC1 domain family member 8B.
      
 0.611
PIANP
PILR alpha associated neural protein.
      
 0.611
AJAP1
Adherens junctions associated protein 1.
      
 0.586
HS3ST4
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.558
APP
Amyloid beta precursor protein.
   
 0.539
RGS9
Regulator of G protein signaling 9.
      
 0.485
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.