| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATP6V1C1 | DPH3 | ENSAPLP00000002878 | ENSAPLP00000007874 | V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | Diphthamide biosynthesis 3. | 0.675 |
| ATP6V1C1 | SERGEF | ENSAPLP00000002878 | ENSAPLP00000005465 | V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | Secretion regulating guanine nucleotide exchange factor. | 0.849 |
| DPH1 | DPH3 | ENSAPLP00000024049 | ENSAPLP00000007874 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. | Diphthamide biosynthesis 3. | 0.992 |
| DPH1 | DPH5 | ENSAPLP00000024049 | ENSAPLP00000015710 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. | Diphthamide biosynthesis 5. | 0.950 |
| DPH1 | EEF2 | ENSAPLP00000024049 | ENSAPLP00000010272 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. | Eukaryotic translation elongation factor 2. | 0.916 |
| DPH1 | ELP3 | ENSAPLP00000024049 | ENSAPLP00000031631 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | 0.634 |
| DPH1 | ENSAPLP00000016515 | ENSAPLP00000024049 | ENSAPLP00000016515 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. | Tr-type G domain-containing protein. | 0.916 |
| DPH1 | ENSAPLP00000022995 | ENSAPLP00000024049 | ENSAPLP00000022995 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. | Uncharacterized protein. | 0.994 |
| DPH1 | SERGEF | ENSAPLP00000024049 | ENSAPLP00000005465 | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. | Secretion regulating guanine nucleotide exchange factor. | 0.492 |
| DPH3 | ATP6V1C1 | ENSAPLP00000007874 | ENSAPLP00000002878 | Diphthamide biosynthesis 3. | V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | 0.675 |
| DPH3 | DPH1 | ENSAPLP00000007874 | ENSAPLP00000024049 | Diphthamide biosynthesis 3. | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. | 0.992 |
| DPH3 | DPH5 | ENSAPLP00000007874 | ENSAPLP00000015710 | Diphthamide biosynthesis 3. | Diphthamide biosynthesis 5. | 0.861 |
| DPH3 | EEF2 | ENSAPLP00000007874 | ENSAPLP00000010272 | Diphthamide biosynthesis 3. | Eukaryotic translation elongation factor 2. | 0.842 |
| DPH3 | ELP1 | ENSAPLP00000007874 | ENSAPLP00000027553 | Diphthamide biosynthesis 3. | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | 0.857 |
| DPH3 | ELP3 | ENSAPLP00000007874 | ENSAPLP00000031631 | Diphthamide biosynthesis 3. | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | 0.896 |
| DPH3 | ENSAPLP00000016515 | ENSAPLP00000007874 | ENSAPLP00000016515 | Diphthamide biosynthesis 3. | Tr-type G domain-containing protein. | 0.842 |
| DPH3 | ENSAPLP00000022995 | ENSAPLP00000007874 | ENSAPLP00000022995 | Diphthamide biosynthesis 3. | Uncharacterized protein. | 0.998 |
| DPH3 | NMB | ENSAPLP00000007874 | ENSAPLP00000017011 | Diphthamide biosynthesis 3. | Uncharacterized protein. | 0.859 |
| DPH3 | SERGEF | ENSAPLP00000007874 | ENSAPLP00000005465 | Diphthamide biosynthesis 3. | Secretion regulating guanine nucleotide exchange factor. | 0.956 |
| DPH5 | DPH1 | ENSAPLP00000015710 | ENSAPLP00000024049 | Diphthamide biosynthesis 5. | 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. | 0.950 |