PRRX2 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PRRX2

Paired related homeobox 2. (141 aa)

Predicted Functional Partners:

FKBP10

0.788

COL6A1

0.769

POSTN

0.752

TGFB3

0.739

TIMP2

0.737

THBS1

0.715

EFEMP1

0.683

FBN1

0.681

ENSAPLP00000025521

0.671

TIMP3

0.670

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COL6A1	EFEMP1	ENSAPLP00000031517	ENSAPLP00000001265	VWFA domain-containing protein.	EGF containing fibulin extracellular matrix protein 1.	0.596
COL6A1	ENSAPLP00000025521	ENSAPLP00000031517	ENSAPLP00000025521	VWFA domain-containing protein.	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	0.562
COL6A1	FBN1	ENSAPLP00000031517	ENSAPLP00000005379	VWFA domain-containing protein.	Fibrillin 1.	0.573
COL6A1	FKBP10	ENSAPLP00000031517	ENSAPLP00000030080	VWFA domain-containing protein.	Peptidylprolyl isomerase.	0.808
COL6A1	POSTN	ENSAPLP00000031517	ENSAPLP00000030565	VWFA domain-containing protein.	Periostin.	0.722
COL6A1	PRRX2	ENSAPLP00000031517	ENSAPLP00000007880	VWFA domain-containing protein.	Paired related homeobox 2.	0.769
COL6A1	TGFB3	ENSAPLP00000031517	ENSAPLP00000011986	VWFA domain-containing protein.	Transforming growth factor beta 3.	0.652
COL6A1	THBS1	ENSAPLP00000031517	ENSAPLP00000022073	VWFA domain-containing protein.	Thrombospondin 1.	0.759
COL6A1	TIMP2	ENSAPLP00000031517	ENSAPLP00000008390	VWFA domain-containing protein.	TIMP metallopeptidase inhibitor 2.	0.714
COL6A1	TIMP3	ENSAPLP00000031517	ENSAPLP00000020135	VWFA domain-containing protein.	TIMP metallopeptidase inhibitor 3.	0.651
EFEMP1	COL6A1	ENSAPLP00000001265	ENSAPLP00000031517	EGF containing fibulin extracellular matrix protein 1.	VWFA domain-containing protein.	0.596
EFEMP1	ENSAPLP00000025521	ENSAPLP00000001265	ENSAPLP00000025521	EGF containing fibulin extracellular matrix protein 1.	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	0.410
EFEMP1	FKBP10	ENSAPLP00000001265	ENSAPLP00000030080	EGF containing fibulin extracellular matrix protein 1.	Peptidylprolyl isomerase.	0.876
EFEMP1	POSTN	ENSAPLP00000001265	ENSAPLP00000030565	EGF containing fibulin extracellular matrix protein 1.	Periostin.	0.604
EFEMP1	PRRX2	ENSAPLP00000001265	ENSAPLP00000007880	EGF containing fibulin extracellular matrix protein 1.	Paired related homeobox 2.	0.683
EFEMP1	TGFB3	ENSAPLP00000001265	ENSAPLP00000011986	EGF containing fibulin extracellular matrix protein 1.	Transforming growth factor beta 3.	0.579
EFEMP1	THBS1	ENSAPLP00000001265	ENSAPLP00000022073	EGF containing fibulin extracellular matrix protein 1.	Thrombospondin 1.	0.631
EFEMP1	TIMP2	ENSAPLP00000001265	ENSAPLP00000008390	EGF containing fibulin extracellular matrix protein 1.	TIMP metallopeptidase inhibitor 2.	0.586
EFEMP1	TIMP3	ENSAPLP00000001265	ENSAPLP00000020135	EGF containing fibulin extracellular matrix protein 1.	TIMP metallopeptidase inhibitor 3.	0.425
ENSAPLP00000025521	COL6A1	ENSAPLP00000025521	ENSAPLP00000031517	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	VWFA domain-containing protein.	0.562