STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCDC6Coiled-coil domain containing 6. (324 aa)    
Predicted Functional Partners:
PPP4R1
Protein phosphatase 4 regulatory subunit 1.
    
 
 0.862
ENSAPLP00000018736
WRNPLPNID domain-containing protein.
    
 
 0.862
ENSAPLP00000018477
Metallophos domain-containing protein.
    
 
 0.834
PPP4R2
Protein phosphatase 4 regulatory subunit 2.
    
 
 0.828
C1S
Complement C1s; Belongs to the peptidase S1 family.
    
   0.819
FBXO42
F-box protein 42.
    
 
 0.720
ENSAPLP00000031367
F-box domain-containing protein.
    
 
 0.720
ENSAPLP00000017036
Uncharacterized protein.
    
 
 0.672
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
      
 0.665
CCDC68
Coiled-coil domain containing 68.
      
 0.664
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.