LRP5 protein (Anas platyrhynchos) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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[Homology]

Score

LRP5

Uncharacterized protein. (471 aa)

Predicted Functional Partners:

DKK2

0.995

SOST

0.994

LRP6

0.992

FZD4

0.992

FZD8

0.985

FZD5

0.985

WNT1

0.982

FZD7

0.976

FZD2

0.976

FZD1

0.976

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DKK2	FZD1	ENSAPLP00000005731	ENSAPLP00000006131	Dickkopf_N domain-containing protein.	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	0.496
DKK2	FZD2	ENSAPLP00000005731	ENSAPLP00000001604	Dickkopf_N domain-containing protein.	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.	0.491
DKK2	FZD4	ENSAPLP00000005731	ENSAPLP00000031545	Dickkopf_N domain-containing protein.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.408
DKK2	FZD5	ENSAPLP00000005731	ENSAPLP00000032188	Dickkopf_N domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.422
DKK2	FZD7	ENSAPLP00000005731	ENSAPLP00000001053	Dickkopf_N domain-containing protein.	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	0.416
DKK2	FZD8	ENSAPLP00000005731	ENSAPLP00000030062	Dickkopf_N domain-containing protein.	Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family.	0.495
DKK2	LRP5	ENSAPLP00000005731	ENSAPLP00000007976	Dickkopf_N domain-containing protein.	Uncharacterized protein.	0.995
DKK2	LRP6	ENSAPLP00000005731	ENSAPLP00000012018	Dickkopf_N domain-containing protein.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.991
DKK2	SOST	ENSAPLP00000005731	ENSAPLP00000028420	Dickkopf_N domain-containing protein.	Sclerostin.	0.711
DKK2	WNT1	ENSAPLP00000005731	ENSAPLP00000028080	Dickkopf_N domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.502
FZD1	DKK2	ENSAPLP00000006131	ENSAPLP00000005731	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Dickkopf_N domain-containing protein.	0.496
FZD1	FZD5	ENSAPLP00000006131	ENSAPLP00000032188	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.521
FZD1	FZD8	ENSAPLP00000006131	ENSAPLP00000030062	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family.	0.521
FZD1	LRP5	ENSAPLP00000006131	ENSAPLP00000007976	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.976
FZD1	LRP6	ENSAPLP00000006131	ENSAPLP00000012018	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.	0.984
FZD1	WNT1	ENSAPLP00000006131	ENSAPLP00000028080	Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.950
FZD2	DKK2	ENSAPLP00000001604	ENSAPLP00000005731	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.	Dickkopf_N domain-containing protein.	0.491
FZD2	FZD5	ENSAPLP00000001604	ENSAPLP00000032188	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.521
FZD2	FZD8	ENSAPLP00000001604	ENSAPLP00000030062	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family.	0.521
FZD2	LRP5	ENSAPLP00000001604	ENSAPLP00000007976	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.976