STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
U3IL57_ANAPPVacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (164 aa)    
Predicted Functional Partners:
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 0.962
SNX12
Sorting nexin 12.
   
 0.945
VPS26A
VPS26, retromer complex component A.
   
 0.932
VPS26B
VPS26, retromer complex component B.
   
 0.932
TBC1D5
TBC1 domain family member 5.
    
 0.885
RAB7A
RAB7A, member RAS oncogene family.
   
 0.861
VPS26C
VPS26 endosomal protein sorting factor C.
   
 
 0.856
CCDC93
Coiled-coil domain containing 93.
    
 
 0.835
FAM45A
UDENN domain-containing protein.
   
 
 0.830
VPS35L
VPS35 endosomal protein sorting factor like.
    
 
 0.828
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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