Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARHGAP45Rho GTPase activating protein 45. (1156 aa)    
Predicted Functional Partners:
UBASH3A
Ubiquitin associated and SH3 domain containing A.
      
 0.739
FAM174C
Family with sequence similarity 174 member C.
    
 
 0.640
CDC42
Cell division cycle 42.
   
 0.626
WDR18
WD repeat domain 18.
      
 0.608
POLR2E
RNA polymerase II subunit E.
      
 0.587
RBIS
Ribosomal biogenesis factor.
      
 0.581
TMEM259
Transmembrane protein 259.
      
 0.577
MIDN
Midnolin.
      
 0.571
LRRCC1
Leucine rich repeat and coiled-coil centrosomal protein 1.
     
 0.560
AHCTF1
AT-hook containing transcription factor 1.
      
 0.554
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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